A rather unusual case of nicotine poisoning occurred lately in a Parisian suburb. The victim, a man in the prime of life, had been cleaning his pipe with a clasp knife. With this he accidentally cut one of his fingers subsequently, but as the wound was of a trivial nature, he paid no heed to it. Five or six hours later, however, the cut finger grew painful and became much swollen. The inflammation rapidly spread to the arm and shoulder, the patient suffering such intense pain that he was obliged to betake himself to his bed. Medical assistance was called in and the ordinary remedies applied, ineffectually. The man, when questioned as to the manner in which he had cut himself, explained the use to which the pocket knife had been applied, adding that he had omitted to wipe it after cleaning his pipe. The apparent mystery which surrounded the case was thus cleared up, and, as the patient's state had become alarming, he was conveyed to the hospital. Upon his admission, the doctors declared that, in the immediate amputation of the arm, lay the only hope of saving the patient's life. The poisoned member was therefore amputated; but in spite of the promptitude with which the operation was performed, the man lies in so precarious a condition, that the chances of his recovery are said to be slight.