Deuteronomy 7:1
When the LORD thy God shall bring thee into the land whither thou goest to possess it, and hath cast out many nations before thee, the Hittites, and the Girgashites, and the Amorites, and the Canaanites, and the Perizzites, and the Hivites, and the Jebusites, seven nations greater and mightier than thou;
The speaker is Christ as Israel's invisible leader, guide, protector and physician, veiled in the pillar of cloud, the same one who later healed the sick in Palestine. He Himself promises to bring Israel into the land to possess it and to cast out many nations before them. The promise names seven nations greater and mightier than Israel — the Hittites, Girgashites, Amorites, Canaanites, Perizzites, Hivites and Jebusites — whom the Lord will bring them in against and drive out. Their possession therefore rests on God's own action and enabling rather than on their strength, for He enables them to dispossess nations stronger than they are.
Israel was to occupy the territory God specified and, as they increased, extend their borders further into land held by nations violating God's law. The verse belongs to the instruction in Deuteronomy 4 through 8 showing what God required for Israel to be a holy people to Himself, namely to keep and do His commandments, statutes and judgments. Their calling is as a holy, specially chosen people, chosen not for size or merit but because God loved them and kept His oath to their fathers.
Because the nations' defeat is God's act, Israel must deal with them as God directs: make no covenant or intermarriage with them and destroy their altars and idols, since their idolatrous worship would turn Israel away from God. The command was given to protect Israel's safety and happiness, lest idolatry draw them away. It stands as part of the call to remain separate from the world and faithful to God's commandments.
God's bringing Israel in and casting out the nations is an act of love and covenant mercy toward those who love Him and keep His commandments to a thousand generations. Obedience brings His covenant and mercy, love, blessing, multiplication, life, possession of the land, prosperity and the removal of all sickness and preservation from disease. God will deal with the nations and let His blessing be seen before all peoples when His people place themselves in right relation to Him so He can work on minds.
Through obedient worship and conduct Israel was to restore God's moral image in humanity and reveal His glory among the nations, preparing the way for Christ's kingdom to extend over the whole earth. The passage is to be studied now because the world is nearing God's great final review, when people must stand before the Judge of all the earth, the present time of investigation when every character is investigated and every case decided for eternity. God respects the obedient and requires commandment keeping in this life as the condition for entering the heavenly city, so no disobedient father, mother or child will be brought in to spoil heaven with a second rebellion. Only tried commandment keepers who love God supremely will be translated, the dead will be raised at Christ's coming, and the nations that have kept the truth will enter through the gates of the holy city to see the King in His beauty and be welcomed with God's blessing resting upon them.