Genesis 42:36
And Jacob their father said unto them, Me have ye bereaved of my children: Joseph is not, and Simeon is not, and ye will take Benjamin away: all these things are against me. And Jacob their father said unto them, Me have ye bereaved of my children: Joseph is not, and Simeon is not, and ye will take Benjamin away: all these things are against me.
Jacob spoke while grieving what he took to be the loss of Joseph and of Simeon, and fearing that Benjamin also would be taken away from him. The money found in his sons' sacks added to his distress at that moment. In saying that all these things were against him, he expressed his sense that losses and present danger had gathered against him and his family as a single burden of sorrow and apprehension.
He refused to let Benjamin go to Egypt. He held Benjamin back because he believed Joseph was dead and Benjamin was his only son left with him. Reuben's rash promise did not ease his fear.
In reality the things he mourned were not against him but were working together for his good. The verse illustrates how people in trial who are governed by appearances and filled with discontent mistake apparent failure and loss for defeat and for God's providence working against them. It teaches that those who follow their own inclinations, contend with God's providence, and remain dissatisfied as though circumstances were arranged to tempt and destroy them are not good judges of God's work.
Such discontented people see failure where there is triumph and great loss where there is gain, complaining against the very pruning and purifying suffering that fits them for heaven by consuming dross until they reflect the divine image. Later Jacob no longer complained about those painful days or viewed his trials as against him, but his memory rested on God's mercy and loving-kindness in preserving and supporting him throughout his life.