Isaiah 19:16

In that day shall Egypt be like unto women: and it shall be afraid and fear because of the shaking of the hand of the LORD of hosts, which he shaketh over it.

Isaiah 19:16 belongs to the first part of Isaiah, chapters 1 to 39, which is made up of single, distinct prophecies and historical accounts from Isaiah's active public ministry among rulers and people, published at different times and on different occasions and afterward gathered into one collection, in contrast to chapters 40 to 66 from his later years which deal wholly with the future. It belongs to the burden or prophecy concerning Egypt. It presents Egypt as one of the nations upon which God brings judgment. It is part of Isaiah 19's foretelling of the future revolutions and condition of Egypt.

It means Egypt would become timid like women, afraid and fearful because of the shaking of the hand of the LORD of hosts over it. That fear would come through invasion, conquest, plundering, falling permanently into the hand of strangers, becoming the lowest of kingdoms, and renouncing idolatry, fulfilled over more than twenty-four centuries through successive subjugation by Babylon under Nebuchadnezzar, Persia under Cambyses, Macedonia under Alexander the Great, Rome, and afterward Saracens, Mamelukes, and Turks. At least part of the chapter's prophecy has already been fulfilled in Egypt. The verse was accomplished centuries ago and has nothing left to be fulfilled in modern times. The prophecy to which the verse belongs was fulfilled in the preaching of the gospel in Egypt and Assyria in New Testament times.