Jeremiah 16:10
And it shall come to pass, when thou shalt shew this people all these words, and they shall say unto thee, Wherefore hath the LORD pronounced all this great evil against us? or what is our iniquity? or what is our sin that we have committed against the LORD our God?
Jeremiah 16:10 belongs to Jeremiah 3 through 21, prophecies whose meaning is clearly understood and whose work is to denounce sin sternly and awfully. That denunciation is uttered with sorrow of heart over the people's transgression, as an earnest and touching appeal for them to return to God. The appeal was met by the mass of the people with a complete lack of response that is both painful and strange.