Jeremiah 18:16
To make their land desolate, and a perpetual hissing; every one that passeth thereby shall be astonished, and wag his head. To make their land desolate, and a perpetual hissing; every one that passeth thereby shall be astonished, and wag his head.
Jeremiah 18:16 is part of a denunciation of Jerusalem. It belongs to a warning whose outcome depends on the people's choices and their response to God. The judgment comes because God's people forgot Him, turned to idolatry, and abandoned the ancient paths for ways away from the ancient way. It shows the consequence of following one's own counsel instead of God's way.
Their land would be made desolate and a lasting object of scorn, a desolation and perpetual hissing. Everyone passing by would be astonished and wag the head at their public disgrace.