Luke 13:33
Nevertheless I must walk to day, and to morrow, and the day following: for it cannot be that a prophet perish out of Jerusalem. Nevertheless I must walk to day, and to morrow, and the day following: for it cannot be that a prophet perish out of Jerusalem.
Certain Pharisees came to Jesus telling Him to get out and depart because Herod would kill Him. They offered that warning as intimidation after His teaching about the strait gate amazed them and they determined to get rid of Him. He refused to be frightened away from His course.
He declared that He must keep walking today and tomorrow and the day following, continuing day by day undeterred by Herod. That appointed walk was to keep casting out devils and doing cures until He is perfected. The reason He gave is that as a prophet His death belongs to Jerusalem, which had made itself the place where a prophet must perish, the city that kills the prophets.
The Lord had risen up early and sent His prophets with messages of warning and reproof and of consolation and promise, but Jerusalem beat one and stoned another. For ages Judah had been the repository of sacred truth where the knowledge of God was cherished while the nations lost it, where prayer and praise ascended from the temple and the bleeding sacrifice pointed to the Lamb of God who takes away sin, yet the divine light was persistently rejected. Teachers in Israel closed their eyes so they would not see and their ears so they would not hear, rejecting light and life and thereby loading upon themselves a cloud of vengeance that would burst in the destruction of Jerusalem.
Approaching Jerusalem for the last time, Christ wept over the rejecters of His mercy after every experiment of mercy and grace. That mercy culminated in sending His Son clothed in humanity to carry a rebellious people on His heart. Their continued rejection filled up the measure of guilt so that the irrevocable sentence falls that their house is left desolate.